This journal publishes original research papers of reasonable permanent intellectual value, in the areas of computer modeling in engineering & Sciences, including, but not limited to computational mechanics, computational materials, computational mathematics, computational physics, computational chemistry, and computational biology, pertinent to solids, fluids, gases, biomaterials, and other continua spanning from various spatial length scales (quantum, nano, micro, meso, and macro), and various time scales (picoseconds to hours) are of interest. Papers which deal with multi-physics problems, as well as those which deal with the interfaces of mechanics, chemistry, and biology, are particularly encouraged. Novel computational approaches and state-of-the-art computation algorithms, such as soft computing, artificial intelligence-based machine learning methods, and computational statistical methods are welcome.